أسئلة الهيئة السعودية للتخصصات الصحية | الاحياء الدقيقة (الميكروبيولوجي) (8)

الأخصائيين

الأحياء الدقيقة  (الميكروبيولوجي) (8)

Match each of the following concepts with its appropriate answer

1.   Following are the test organisms used for the I.P microbiological assay of
antibiotics match them correctly:

Colum A		Answer	Colum B
1	Rifampicin	D	A	Escherichia Coli
2	Tetracyclin	E	B	Klebsiella pneumonia
3	Streptomycin	A	C	Micrococcus luteus
4	Chloramphenol	A	D	Bacillus subtilis
			E	Bacillus cereus

2.  The drugs mentioned below are produced by the species mentioned from A to E. Match them correctly :

Colum A		Answer	Colum B
1	Rifampicin	C	A	Streptomyces griseus
2	Nystatin	E	B	Bacillus polymyxa
3	Amphotericin B	D	C	Streptomyces mediterranei
4	Candicidin	B	D	Streptomyces nodosus
			E	Streptomyces noursei

3.  Match the correct method of sterilization listed A to E for the following drugs :

Colum A		Answer	Colum B
1	Tetracyclin injection	D	A	Sterilised by dry heat
2	Insulin injection	C	B	Sterilised by heating with a bacteria
3	Quinine injection	E	C	Sterilised by aseptic method
4	Morphine injection	B	D	Prepared by aseptic method
			E	Sterilised by heating in an autoclave

4.  Match the following rickettsial disease with their respective organisms:

Colum A		Answer	Colum B
1	Epidemic typhus	B	A	Rickettsia rickettsi
2	Scrub typhus	C	B	Rickettsia prowazeki
3	Trench typhus	D	C	Rickettsia typhus
4	Murine typhus	E	D	Rickettsia Quintana
			E	Rickettsia typhus

5.   Match the following antimicrobial with their respective side effects A to E:

Colum A		Answer	Colum B
1	Acridines	E	A	Showed adverse effects on proteins
2	Benzalkonium	C	B	exhibit synergism and chloride unsuitable for preservative in eye drops
3	Parahydroxy	B	C	Haemolytic benzoates
4	Formalin	A	D	Very toxic
			E	Toxic to leucocytes and retard granulation process

6.    Match the following antibiotics with their respective modes of administration A to E:

Colum A		Answer	Colum B
1	Penicillin V	B	A	Intramuscular suspension
2	Benzathine	A	B	Oral penicillin
3	Methicillin sodium	E	C	Both as oral and injection
4	Ampicillin	C	D	Locally applied
			E	Intramuscular injection

7.  Match the following antibiotics with respective strains A to E used for their production :

Colum A		Answer	Colum B
1	Tetracyclin	D	A	Streptomyces erythreus
2	Chloramphenicol	E	B	Streptomyces garyphalous
3	Erythromycin	A	C	Streptomyces niveus
4	Cycloserine	B	D	Streptomyces viridifaciens
			E	Streptomyces venezuelae

8.   Match the following strains with their respective produced antibiotics A to E:

Colum A		Answer	Colum B
1	Streptomyces griseus.	E	A	Oxytetracycline
2	Streptomyces aureofaciens	D	B	Neomycin sulphate
3	Streptomyces rimosus	A	C	Viomycin
4	Streptomyces griseus var. purpurea	C	D	Chlortetracycline
			E	Streptomycin

9.   Match the following antibiotics with their respective disease A to E to be cured :

Colum A		Answer	Colum B
1	Streptomycin	B	A	Staphylococcus infections
2	Cycloserine	D	B	Tuberculosis
3	Novobiocin	A	C	Fungal tuberculosis
4	Griseofulvin	C	D	Pulmonary tuberculosis
			E	Anti-spirochaetes

10.         Match the following antibiotics with their respective side effects A to E:

Colum A		Answer	Colum B
1	Novobiocin	D	A	Damages 8th cramial nerve
2	Neomycin	E	B	Damages CNS
3	Cycloserine	B	C	Damages haemopoietic system
4	Chloramphenol	C	D	Skin rashes
			E	Kidney problems

11.       Match the following antibiotics with their modes of action A to E:

Colum A		Answer	Colum B
1	Tetracyclines	B	A	Form an irreversible complex with sterols
2	Erythromycin	C	B	Chelation of light divalent salts
3	Novobiocin	D	C	Blocks protein synthesis
4	Griseofulvin	E	D	Interferes with the conjugation of bilirubin
			E	Influences mitosis

12.         Match the following dosage forms with their respective antibiotics A to E:

Colum A		Answer	Colum B
1	Tablets	B	A	Vancomycin Hcl
2	Intravenous injection	A	B	Colistin
3	Capsules	E	C	Polymixin B sulphate
4	Intramuscular	C	D	Gentamycin injection
			E	Paromomycin sulphate

13.         Match the following side effects with their respective antibiotics A to E:

Colum A		Answer	Colum B
1	Nephrotoxic	E	A	Triacetyloleandomycin
2	Rashes	A	B	Polymixin B sulphate
3	Hypersensitivity	D	C	Cephaloridine
4	Gastric irritation	B	D	Gentamycin
			E	Sodium fusidate

14.         Match the following antibiotics with their respective activity spectra A to E:

Colum A		Answer	Colum B
1	Bacitracin	E	A	Gram negative
2	Gentamycin	A	B	Mainly staphylococci
3	Sodium fusidate	D	C	Mainly Ps. Aeruginosa
4	Framycetin	B	D	Gram positive
			E	Streptococcus pyogenes

15.       Match the following enzymes with their activities A to E:

Colum A		Answer	Colum B
1	Hyaluronidase	B	A	Inactivate leucocytes and aid bacterial invasion
2	Collagenase	C	B	Reversibly catalyzes the breakdown of a major component
3	Lecithinase	D	C	Disintegrates a constituent of muscle, cartilage and bone
4	Leucocidins	A	D	Haemolysis of erythrocytes and the necrosis of other cells
			E	Clots plasma and surrounds the bacteria

16.          Match the following aggresins with their respective modes of action from A to E:

Colum A		Answer	Colum B
1	Hyaluronidase	B	A	Destroys RBC’s and other tissues
2	Haemolysis	A	B	Breaks down connective tissues, increases permeability of tissue space
3	Streptokinase	D	C	Causes lysis of RBC’s and other tissues
4	Lecithinase	C	D	Digest the fibrin of blood
			E	Dissolves collagen

17.       Match the following terms with their respective effects A to E:

Colum A		Answer	Colum B
1	Brucella melitensis	C	A	Causes trachoma, conjunctivitis and nongonococcal gamets
2	Flavobacterium	B	B	Causes influenza like fever species
3	Chlamydia	A	C	Causes Malta fever in goats trachomatis
4	Leptospira	E	D	Contaminates pharmaceutical icterohaemorrhagiae products
			E	Weil’s disease (jaundice)

يُتبع  Continued