أسئلة الهيئة السعودية للتخصصات الصحية | الاحياء الدقيقة (الميكروبيولوجي) (3)

الأخصائيين

أحياء دقيقة  (ميكروبيولوجي) (3)

1.     Sporozite vaccine in malaria has

a.     Induces antibodies

b.     Prevents only asexual forms with reproduction

c.      No effects on clinical illness

d.     None of the above

2.     Growing trophozoites and schizonts are not seen in the peripheral blood in malaria due to

a.     P. falciparum

b.     P.vivax

c.      P.ovale

d.     P. malaria

3.     Thin blood smear for malaria is used to identify

a.     Plasmodium

b.     Gametocytes

c.      Type of parasite

d.     Schizont

4.     The radical teatment of malaria is to half

a.     Gametocyte

b.     Exo-erythrocytic phase

c.      Erythrocytic phase

d.     All of these

5.     Symptoms of acute aflatoxicosis

a.     Osteogenic sarcoma

b.     Lymphatic leukemia

c.      Malaise & Anorexia

d.     Both a and b

6.     Most important Penicillium toxins are

a.     Citrinin

b.     Patulin

c.      Penicillic acid

d.     All of the above

7.     Penicillic acid is produced by

a.     A. ochraceus

b.     P. puberulum

c.      Both a and b

d.     None of the above

8.     Fungi producting mycelium are called

a.     Moulds

b.     Filamentous fungi

c.      Both a and b

d.     Yeasts

9.     Candidiasis is caused by

a.     Candida albicans

b.     Aspergillus spp.

c.      E. floccosum

d.     M. audouinii

10.                 Candida albicans is capable to form

a.     Single cells

b.     Pseudomonas

c.      Multicellular forms

d.     None of these

11.                 Aspergillus fumigatus can infect

a.     A. niger

b.     A. fumigatus

c.      A. flavus

d.     A. oryzae

12.                 A.fumigates can produce

a.     Endotoxins

b.     Exotoxins

c.      Enterotoxins

d.     None of these

13.                 The drug of choice for dermal, oral and vaginal candidiasis is

a.     Griseofulvin

b.     Amphotericin B

c.      Gentian violet

d.     Nystatin

14.                 The following Penicillium species are pathogenic except

a.     P. commune

b.     P. bicolor

c.      P. glaucum

d.     P.notatum

15.                 143. Tinea versicolor is caused by

a.     Candida albicans

b.     Malassezia furfur

c.      Aspergillus niger

d.     None of these

16.                 Causative agent of Tinea nigra

a.     Malassezia furfur

b.     Exophiala werenekii

c.      Candida albicans

d.     Aspergillus flavus

17.                 Causative agent of African histoplasmosis

a.     Histoplasma capsulatum

b.     Histoplasma duboissi

c.      Aspergillus niger

d.     Aspergillus flavus

18.                 Sun ray fungus is

a.     Actinomyces irraeli

b.     Chromoblastomycosis

c.      Streptomyces griseus

d.     Cryptococcosis

19.                 Which agent on addition to a colony inhibits its growth and on removal the colony regrows is?

a.     Bacteriostatic

b.     Bactericidal

c.      Antibiotic

d.     Antiseptic

20.                 Griseofluvin is obtained from

a.     Penicillium notatum

b.     Streptomyces griseus

c.      Penicillium griseofluvin

d.     None of these

21.                 β-lactum ring is present in

a.     Erythromycin

b.     Penicillin

c.      Tetracyclins

d.     Chloramphenicol

22.                 All of the following drugs act on cell membrane, except

a.     Novobiocin

b.     Nystatin

c.      Chloromycetin

d.     Colicins

23.                 Cycloserine related to the amino acid in structure

a.     Serine

b.     Aspergine

c.      Alanine

d.     None of these

24.                 In Tuberculosis therapy mainly used antibiotic is

a.     Penicillin

b.     Streptomycin

c.      Chloramphenol

d.     Cycloserine

25.                 The antibacterial action of penicillin is due to its effect on

a.     Cell membrane permeability

b.     Cell wall synthesis

c.      DNA synthesis

d.     Protein synthesis

26.                 The antibiotic produced from Bacillus subtilis is

a.     Vancomycin

b.     Bactiracin

c.      Both a and b

d.     None of these

27.                 bacitracin sensitivity test is done for

a.     Pneunocci

b.     Group ‘A’ Streptococci

c.      Gonococci

d.     Staphylococci

28.                 The effect of antibiotics on microorganisms is mainly due to

a.     Inhibition of cell-wall synthesis

b.     Damage to the cytoplasmic membrane

c.      Inhibition of nucleic acid and protein synthesis

d.     All of the above

29.                 The antibiotic acting on cell wall is

a.     Penicillin

b.     Bacitracin

c.      Cyclosporin

d.     All of the above

30.                 Erythromycin belongs to chemical class of antibiotics

a.     â-lactose

b.     Tetracyclines

c.      Macrolides

d.     Aminoglycosides

31.                 Bacterial resistance to antibiotics is transmitted by

a.     Transduction

b.     Transformation

c.      Mutation

d.     Plasmids

32.                 Erythromycin inhibits protein synthesis by

a.     Attaching to 30 S ribosome unit

b.     Attaching to 50 S unit or ribosome

c.      By the attachment to t-RNA

d.     By the attachment to m-RNA

33.                 The function of (THFA) Tetrahydrofolic acid coenzyme include

a.     Amino acid synthesis

b.     Thymidine synthesis

c.      Protein synthesis

d.     Both a and b

34.                 Resistant to drugs in tuberculosis develops by

a.     Transduction

b.     Transformation

c.      Conjugation

d.     Mutation

35. Which of the following is penicillinase resistant acid labile penicillin?

a.     Amoxycillin

b.     Cloxacillin

c.      Carbenicillin

d.     Methicillin

36.                 Which of the following does not inhibit cell wall synthesis?

a.     Penicillin

b.     Carbenicillin

c.      Amikacin

d.     Vancomycin

37.                 The anti tumor antibiotics act by inhibiting

a.     Cell wall synthesis

b.     RNA synthesis

c.      Cell membrane synthesis

d.     The DNA structure & function

38.                 Drug resistance to sulphonamides is due to

a.     Production of PABA

b.     Folic acid synthetase

c.      Drug alteration

d.     Low affinity for drug synthesis by bacteria

39.                 Amoxycillin is combined with clavulanic acid to inhibit

a.     DNA gyrace

b.     Cell synthesis

c.      Protein synthesis

d.     β-lactamase enzymes

40.                 Drug of choice for methicillin resistant staph. Aureus is

a.     Ampicillin

b.     Erythromycin

c.      Neomycin

d.     Vancomycin

41.                 Nalidixic acid activity is due to

a.     The inhibition of DNA synthesis

b.     Inhibition of protein synthesis

c.      The inhibition of cell wall synthesis

d.     Both b and c

42.                 The best test for the susceptibility of a microorganism to antibiotics and other chemotherapeutic agents:

a.     Tube-dilution test

b.     Paper-disc (antibiotic) test

c.      Both a and b

d.     None of these

43.                 The smallest amount of chemotherapeutic agents required to inhibit the growth of the organism in Vitro is known as

a.     MIC (minimum inhibitory concentration)

b.     Thermal death point (TDP)

c.      Death rate

d.     None of these

44.                 Clear-zones formation around antibiotic disc is due to

a.     Growth of the bacterium surrounding of the disc

b.     Lysis of the bacterial cells surrounding the disc

c.      The destruction of paper disc (antibiotic)

d.     None of these

45.                 Bacitracin is obtained from

a.     B. subtilis

b.     B. anthracis

c.      B. cereus

d.     B. anthracoid

46.                 Vancomycin is obtained from

a.     Streptococcus species

b.     Aspergillus niger

c.      Streptomyces orientalis

d.     Bacillus anthracis

47.                 175. â-lactum antibiotics are

a.     Penicillin

b.     Cephalosporin

c.      Both a & b

d.     None of these

48.                 Virus causing mumps is also responsible for

a.     Measles

b.     Hepatitis A

c.      Rabies

d.     Variola

49.  Epidemic pleurodynia and myocarditis of new born infants are both caused by

a.     Group B cox sack virus

b.     Reovirus

c.      Polyomavirus

d.     Cytomegalovirus

50.                 Human papillomavirus causes following tumors:

a.     Hepatic carcinoma

b.     Cervical cancer

c.      Condyloma acuminatum

d.     Plantar wart

يُتبع  Continued